Neuropathic Pain I
	Neuropathic pain
	Neuropathic Pain I: Slide 3
	Neuropathic Pain I: Slide 4
	Neuropathic Pain I: Slide 5
	Pain
	Peripheral
	Central
	Central
	Central
	Central / Long term changes
	Activation of DRG neurons via sympathetic fibres
	Resemblance
	Diabetic neuropathy
	Postherpetic Neuralgia
	Antidepressants
	Antidepressants
	Antidepressants
	Anticonvulsants
	Antidepressants / Anticonvulsants
	Opioids
	Treatments
	Economic evaluation of a therapy or intervention
	The effectiveness of medications for the treatment of neuropathic pain
	Utilities
	Decision Model
	Neuropathic Pain I: Slide 26
	Neuropathic Pain I: Slide 27
	Cost Estimates
	Cost-utility Evaluation
	Modulation of the sympathetic nervous system
	Local anesthetic blockade of the sympathetic chain
	Local anesthetic blockade of the sympathetic chain
	Invasive treatments
	Dorsal root entry zone (DREZ) lesions
	Pre-emptive treatments
	Neuropathic pain

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