1. Session 1: Introduction: course overview – scientific discovery

1.1. Reading

• Lyckholm, L.J. Should physicians accept gifts from patients? JAMA 280:1942-1946, 1998.

• Burnett, J.C. Jr. Biomedical research at Mayo Clinic: A tradition of collaboration and a version for year 2000 and beyond. Mayo Clin Proc 75:337-339, 2000.

• Miller, E. clinical investigators – the endangered species revisited. JAMA 286: 845-846, 2001.

• Gordon, L.E. Mental health of medical students: the culture of objectivity in medicine. The Pharos 59:2-10, 1996.

• Crowley, W.F. Jr., et al. Clinical research in the United States at a crossroads. Proposal for a novel public-private partnership to establish a national clinical research enterprise. JAMA 291:1120-1126, 2004.

• Schwartz, R. S. Paul Ehrlich’s magic bullets. N. Engl. J. Med. 350:1079-1080, 2004.

• Markel, H. “Who’s on first?” – medical discoveries and scientific priority. N. Engl. J. Med. 351:2792-2794, 2004.

• Tinetti, M.E. et al. Potential pitfalls of disease-specific guidelines for patients with multiple conditions. N. Engl. J. Med. 351:2870-2874, 2004.

• Kintishch, E. Researcher faces prison for fraud in NIH grant applications and papers. Science 307:1851, 2005.